Osteitis fibrosa cystica is defined as the classic skeletal manifestation of advanced hyperparathyroidism.
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He was known for his work on congenital juvenile osteochondritis, and contributed to the pathological understanding of osteitis fibrosa cystica and achondroplasia.
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In 1898 he was the first scientist to describe H�rthle cells, and in 1904 he was the first to link osteitis fibrosa cystica with parathyroid tumors.
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